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An evaluation of visual function at doses up to twice the maximum recommended dose revealed no effects of Viagra on visual acuity, intraocular pressure, or pupillometry. Effects of Viagra on Sperm : There was no effect on sperm motility or morphology after single 100 mg oral doses of Viagra in healthy volunteers. Pharmacokinetics. Viagra is rapidly absorbed after oral administration, with a mean absolute bioavailability of 41 (range 25ndash;63). The pharmacokinetics of sildenafil are dose-proportional over the recommended dose range. It is eliminated predominantly by hepatic metabolism (mainly CYP3A4) and is converted to an active metabolite with properties similar to the parent, sildenafil.

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